Cancer Research UK Manchester Institute – 4 Year PhD Studentships Autumn 2025

The Cancer Research UK Manchester Institute [CRUK MI] is a world-leading cancer centre of excellence within The University of Manchester, core funded by Cancer Research UK, the largest independent cancer research organisation in the world. The Institute offers exceptional laboratory facilities underpinned by outstanding core facilities including next generation sequencing, real-time PCR, mass spectrometry, histology, advanced imaging and biological resources unit. Our research programmes span the whole spectrum of cancer research from the molecular and cellular basis of cancer through to those focused on translation research and clinical trials. We are partnered with The Christie NHS Foundation Trust one of the largest cancer treatment centres in Europe which provides a critical link to our mission of improving patient care through translational research. These factors combined provide an exceptional environment in which to pursue a PhD.

Studentships are sponsored fully by Cancer Research UK for 4 years commencing September 2025. Successful applicants will receive a non-taxable annual stipend (living allowance) of £21,000 per annum and funding to fully cover University tuition & bench fees. We have the following five projects available in the following CRUK Manchester Institute research groups:

“Characterising tumour -promoting and -restrictive functions of the microenvironment”

Systems Oncology - Principal Investigator: Claus Jorgensen

“Computational annotation of the evolutionary relationship between metastatic tumour and host environment” (Ian Harty Charitable Trust)

Systems Oncology - Principal Investigator: Claus Jorgensen

“Mapping the extracellular landscapes of DNA and RNA in the blood of cancer patients with liquid biopsy”

Nucleic Acids Biomarkers - Principal Investigator: Florent Mouliere

“Development of Novel Cellular Platforms for Immunotherapies”

Stem Cell Biology - Principal Investigator: Georges Lacaud

“Dissecting the fatty acid-induced epitranscriptome driving cancer malignancies”

RNA Dynamics in Cancer - Principal Investigator: Sylvain Delaunay

"Innovative technologies for exploration of mechanisms of transcription factor function in acute myeloid leukaemia"

Leukaemia Biology - Principal Investigator: Tim Somervaille

We welcome applications from enthusiastic, focused, and ambitious students. Applicants should hold or expected to graduate with a first or minimum upper-second class undergraduate honours degree (or equivalent from a non-UK university) in a relevant subject as part of a university degree course.

The Cancer Research UK Manchester Institute is proud to be a diverse, open, and global Institute. Our priority, and that of the University of Manchester, is to support our current students and welcome new ones from Europe and other continents, we therefore encourage students of all nationalities to apply for our postgraduate programme.
• Application deadline: Friday 22 November 2024, 17:00 hrs (GMT).
• Interview date: Monday 13 January 2025, New Paterson Building, Manchester, UK.
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